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Carcino Embryonic Antigen CEA [JM93-28]

Catalog Number:OM638053
OM638053
Discount Price
OM638053-100ul
1~2 Week
100ul
OM638053-50ul
50ul
OM638053-20ul
20ul
1~2 Week
Product Profile
Product Name Carcino Embryonic Antigen CEA [JM93-28]
Antibody Type Primary Antibodies
Antigen Alias Carcinoembryonic antigen antibody Carcinoembryonic antigen-related cell adhesion molecule 5 antibody CD66e antibody CEA antibody Ceacam5 antibody CEAM5_HUMAN antibody DKFZp781M2392 antibody Meconium antigen 100 antibody OTTHUMP00000199032 antibody OTTHUMP00000199033 antibody OTTHUMP00000199034 antibody
Product description The CD66 (carcinoembryonic antigen, CEA, biliary glycoprotein I, BGP-1, CEACAM) immunoglobulin superfamily of genes encode cell adhesion proteins, which are expressed at higher levels in tumorous tissues than in normal tissues. The human CD66 gene family is a diverse set of glycoproteins of epithelial and hematopoietic lineage that comprises 29 genes, which map to chromosome position 19q13.1-q13.2. CD66A, CD66B, CD66C, CD66D, CD66E and CD66F are the best characterized CD66 antigens, and CD66A-D expression upregulates on the surface of granulocytes upon stimulation. Certain CD66 family members mediate homotypic and heterotypic intercellular adhesion events. CD66E, also known as CEA, is a well known tumor marker and a heavily glycosylated GPI-linked cell surface molecule.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBICC/IFIHC
WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names Carcinoembryonic antigen antibody Carcinoembryonic antigen-related cell adhesion molecule 5 antibody CD66e antibody CEA antibody Ceacam5 antibody CEAM5_HUMAN antibody DKFZp781M2392 antibody Meconium antigen 100 antibody OTTHUMP00000199032 antibody OTTHUMP00000199033 antibody OTTHUMP00000199034 antibody
Molecular Weight(MW) 76 kDa
Cellular Localization Membrane.
Database Links
SwissProt ID P06731
Application

Application

Fig1: ICC staining Carcino Embryonic Antigen CEA(CD66e) in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig2: ICC staining Carcino Embryonic Antigen CEA(CD66e) in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-Carcino Embryonic Antigen CEA(CD66e) antibody. Counter stained with hematoxylin.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue using anti-Carcino Embryonic Antigen CEA(CD66e) antibody. Counter stained with hematoxylin.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-Carcino Embryonic Antigen CEA(CD66e) antibody. Counter stained with hematoxylin.
Positive Control HUVEC, MCF-7, human lung cancer tissue, human stomach cancer tissue, human colon cancer tissue.
Application Notes WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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