Application
Fig1: Western blot analysis of cbx7 on A431 cell using anti-cbx7 antibody at 1/1,000 dilution.Application
Fig2: Flow cytometric analysis of Hela cells with cbx7 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).| Product Name | cbx7 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Cbx 7 antibody CBX7 antibody Chromobox homolog 7 antibody Chromobox protein homolog 7 antibody |
| Product description | CBX7 (Chromobox protein homolog 7) is a 251 amino acid nuclear protein that contains one N-terminal chromo domain and one C-terminal Pc box. Highly expressed in kidney, brain, heart and skeletal muscle, with weaker expression in peripheral blood leukocytes, CBX7 functions as a component of the chromatin-associated polycomb complex (PcG) and is involved in maintaining the transcriptionally repressed state of target genes. Additionally, CBX7 modifies chromatin and is thought to extend the cellular life span of epithelial cells by repressing p14 ARF expression, while simultaneously repressing telomerase activity. Due to its ability to repress the transcription of cell-cycle related proteins, CBX7 is thought to play a role in tumorigenesis, specifically in the development of follicular lymphoma and thyroid cancer. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBFC |
| WB:1:500-1:2,000 FC:1:50-1:100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Cbx 7 antibody CBX7 antibody Chromobox homolog 7 antibody Chromobox protein homolog 7 antibody |
|---|---|
| Cellular Localization | Nucleus. |
| SwissProt ID | O95931 |
|---|
Application
Fig1: Western blot analysis of cbx7 on A431 cell using anti-cbx7 antibody at 1/1,000 dilution.
Application
Fig2: Flow cytometric analysis of Hela cells with cbx7 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).| Positive Control | A431, Hela. |
|---|---|
| Application Notes | WB:1:500-1:2,000 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
