Application
Fig1: Western blot analysis of MMP3 on different lysates using anti-MMP3 antibody at 1/1,000 dilution. Positive control: Lane 1: Human liver Lane 2: Mouse lung Lane 3: Rat liverApplication
Fig2: Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-MMP3 antibody. Counter stained with hematoxylin.Application
Fig3: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-MMP3 antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-MMP3 antibody. Counter stained with hematoxylin.Application
Fig5: Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-MMP3 antibody. Counter stained with hematoxylin.| Product Name | MMP3 |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, -2 and -3 respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2,000 IHC:1:50-1:200 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Alternative Names | CHDS6 antibody Matrix metalloproteinase 3 antibody Matrix metalloproteinase-3 antibody MGC126102 antibody MGC126103 antibody MGC126104 antibody MMP 3 antibody MMP-3 antibody MMP3 antibody MMP3_HUMAN antibody Proteoglycanase antibody SL-1 antibody SL1 antibody STMY antibody STMY1 antibody STR1 antibody Stromelysin 1 antibody Stromelysin-1 antibody Transin 1 antibody Transin-1 antibody |
|---|---|
| Cellular Localization | Secreted, extracellular space. |
Application
Fig1: Western blot analysis of MMP3 on different lysates using anti-MMP3 antibody at 1/1,000 dilution. Positive control: Lane 1: Human liver Lane 2: Mouse lung Lane 3: Rat liver
Application
Fig2: Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-MMP3 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-MMP3 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-MMP3 antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-MMP3 antibody. Counter stained with hematoxylin.| Positive Control | Human liver tissue, mouse lung tissue lysate, rat liver tissue lysate, rat kidney tissue, human placenta tissue, mouse liver tissue. |
|---|---|
| Application Notes | WB:1:500-1:2,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
