Application
Fig1: Western blot analysis of Alpha Fodrin on different lysates using anti-Alpha Fodrin antibody at 1/500 dilution. Positive control: Lane 1: Hela Lane 2: Jurkat Lane 3: NIH-3T3 Lane 4:Rat brain Lane 5:Mouse brainApplication
Fig2: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Alpha Fodrin antibody. Counter stained with hematoxylin.Application
Fig3: Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-Alpha Fodrin antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue using anti-Alpha Fodrin antibody. Counter stained with hematoxylin.| Product Name | Alpha Fodrin [JU32-09] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | (ALPHA)II-SPECTRIN antibody Alpha II Spectrin antibody Alpha-II spectrin antibodybrain antibody EIEE5 antibody FLJ17738 antibody FLJ44613 antibody Fodrin alpha chain antibody Fodrin, alpha antibody NEAS antibody Non erythrocytic spectrin alpha antibody non-erythroid alpha chain antibody SPECA antibody Spectrin alpha chain antibody Spectrin alpha chain brain antibody Spectrin alpha non erythrocytic 1 antibody Spectrin antibody Spectrin non erythroid alpha chain antibody Spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) antibody Spectrin, nonerythroid, alpha subunit antibody Spna2 antibody SPTA 2 antibody SPTA2 antibody SPTA2_HUMAN antibody SPTAN 1 antibody SPTAN1 antibody |
| Product description | Alpha Fodrin also named Spectrin. Spectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous α and β chains, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. Spectrin α I and spectrin β I are present in erythrocytes, whereas spectrin α II (also designated fodrin α) and spectrin β II (also designated fodrin β) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Activation of calpain results in the breakdown of spectrin α II, a neuronal cytoskeleton protein. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2,000 IHC:1:50-1:200 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | (ALPHA)II-SPECTRIN antibody
Alpha II Spectrin antibody
Alpha-II spectrin antibodybrain antibody
EIEE5 antibody
FLJ17738 antibody
FLJ44613 antibody
Fodrin alpha chain antibody
Fodrin alpha antibody NEAS antibody Non erythrocytic spectrin alpha antibody non-erythroid alpha chain antibody SPECA antibody Spectrin alpha chain antibody Spectrin alpha chain brain antibody Spectrin alpha non erythrocytic 1 antibody Spectrin antibody Spectrin non erythroid alpha chain antibody Spectrin alpha non-erythrocytic 1 (alpha-fodrin) antibody Spectrin nonerythroid alpha subunit antibody Spna2 antibody SPTA 2 antibody SPTA2 antibody SPTA2_HUMAN antibody SPTAN 1 antibody SPTAN1 antibody |
|---|---|
| Molecular Weight(MW) | 285/150 kDa |
| Cellular Localization | Cytoskeleton. |
Application
Fig1: Western blot analysis of Alpha Fodrin on different lysates using anti-Alpha Fodrin antibody at 1/500 dilution. Positive control: Lane 1: Hela Lane 2: Jurkat Lane 3: NIH-3T3 Lane 4:Rat brain Lane 5:Mouse brain
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Alpha Fodrin antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-Alpha Fodrin antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue using anti-Alpha Fodrin antibody. Counter stained with hematoxylin.| Positive Control | Hela, NIH-3T3, Jurkat, rat brain tissue lysate, mouse brain tissue, human liver cancer tissue, human pancreas tissue, mouse cerebellum tissue. |
|---|---|
| Application Notes | WB:1:500-1:2,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
