Application
Fig1: ICC staining MMP17 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.Application
Fig2: ICC staining MMP17 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.Application
Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-MMP17 antibody. Counter stained with hematoxylin.| Product Name | MMP17 [JU33-03] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Matrix metalloproteinase 17 antibody Matrix metalloproteinase 17 membrane inserted antibody Matrix metalloproteinase-17 antibody Membrane type 4 matrix metalloproteinase antibody Membrane type matrix metalloproteinase 4 antibody Membrane-type matrix metalloproteinase 4 antibody Membrane-type-4 matrix metalloproteinase antibody MMP 17 antibody MMP-17 antibody Mmp17 antibody MMP17_HUMAN antibody MT MMP 4 antibody MT MMP4 antibody MT-MMP 4 antibody MT4 MMP antibody MT4-MMP antibody MT4MMP antibody MTMMP 4 antibody MTMMP4 antibody |
| Product description | Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin. |
| Immunogen | Recombinant protein within human MMP17 aa 1-250. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | ICCIFIHCWB |
| ICC:1:50 IHC:1:50 WB:1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | Matrix metalloproteinase 17 antibody Matrix metalloproteinase 17 membrane inserted antibody Matrix metalloproteinase-17 antibody Membrane type 4 matrix metalloproteinase antibody Membrane type matrix metalloproteinase 4 antibody Membrane-type matrix metalloproteinase 4 antibody Membrane-type-4 matrix metalloproteinase antibody MMP 17 antibody MMP-17 antibody Mmp17 antibody MMP17_HUMAN antibody MT MMP 4 antibody MT MMP4 antibody MT-MMP 4 antibody MT4 MMP antibody MT4-MMP antibody MT4MMP antibody MTMMP 4 antibody MTMMP4 antibody |
|---|---|
| Molecular Weight(MW) | 67 kDa |
| Cellular Localization | Secreted. Plasma membrane. |
Application
Fig1: ICC staining MMP17 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig2: ICC staining MMP17 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-MMP17 antibody. Counter stained with hematoxylin.| Positive Control | A549, MCF-7, mouse brain tissue. |
|---|---|
| Application Notes | ICC:1:50 IHC:1:50 WB:1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
