Application
Fig1: Western blot analysis of DDX6 on different lysates using anti-DDX6 antibody at 1/500 dilution. Positive control: Lane 1: Human colon Lane 2: SH-SY-5Y Lane 3: SiHa Lane 4: K562Application
Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-DDX6 antibody. Counter stained with hematoxylin.Application
Fig3: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-DDX6 antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue using anti-DDX6 antibody. Counter stained with hematoxylin.Application
Fig5: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-DDX6 antibody. Counter stained with hematoxylin.| Product Name | DDX6 [JB41-32] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ATP dependent RNA helicase DDX6 antibody ATP dependent RNA helicase p54 antibody DDX6 antibody DEAD (Asp Glu Ala Asp) box polypeptide 6 antibody DEAD box 6 antibody DEAD box protein 6 antibody DEAD/H (Asp Glu Ala Asp/His) box polypeptide 6 (RNA helicase 54kD) antibody FLJ36338 antibody HLR2 antibody Oncogene RCK antibody P54 antibody Probable ATP-dependent RNA helicase DDX6 antibody RCK antibody |
| Product description | RCK, also known as DDX6 and P54, is a member of the DEAD-box RNA helicase family of proteins, all of which share common protein motifs. Found in most tissues, RCK is an unwindase that exhibits ATP-dependent RNA un-winding activity, as well as the ability to decay RNA in the 5'-3' direction. In non-malignant cells, RCK is associated with all processes of normal RNA metabolism including splicing, export and translation initiation. Mutations in the gene encoding RCK can cause the protein to be overexpressed, changing its function to that of an oncogene that positively regulates the expression of genes involved in cell growth and proliferation. It is believed that, through its unwindase activity, the main function of RCK is to downregulate mRNA expression and maintain normal transcriptional levels within the cell. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:1,000 IHC:1:50-1:100 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | ATP dependent RNA helicase DDX6 antibody ATP dependent RNA helicase p54 antibody DDX6 antibody DEAD (Asp Glu Ala Asp) box polypeptide 6 antibody DEAD box 6 antibody DEAD box protein 6 antibody DEAD/H (Asp Glu Ala Asp/His) box polypeptide 6 (RNA helicase 54kD) antibody FLJ36338 antibody HLR2 antibody Oncogene RCK antibody P54 antibody Probable ATP-dependent RNA helicase DDX6 antibody RCK antibody |
|---|---|
| Molecular Weight(MW) | 54 kDa |
| Cellular Localization | Cytoplasm. Nucleus. |
Application
Fig1: Western blot analysis of DDX6 on different lysates using anti-DDX6 antibody at 1/500 dilution. Positive control: Lane 1: Human colon Lane 2: SH-SY-5Y Lane 3: SiHa Lane 4: K562
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-DDX6 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-DDX6 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue using anti-DDX6 antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-DDX6 antibody. Counter stained with hematoxylin.| Positive Control | Rat brain tissue, human tonsil tissue, human kidney tissue, mouse small intestine tissue, human colon tissue, SH-SY-5Y, K562, SiHa. |
|---|---|
| Application Notes | WB:1:500-1:1,000 IHC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
