Application
Fig1:Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-LY75 antibody. Counter stained with hematoxylin.Application
Fig2: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-LY75 antibody. Counter stained with hematoxylin.Application
Fig3: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-LY75 antibody. Counter stained with hematoxylin.Application
Fig4:Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-LY75 antibody. Counter stained with hematoxylin.| Product Name | LY75 [JB87-35] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C-type lectin domain family 13 member B antibody CD 205 antibody CD205 antibody CD205 antigen antibody CLEC 13B antibody CLEC13B antibody DEC 205 antibody DEC-205 antibody DEC205 antibody gp200 antibody gp200 MR6 antibody gp200-MR6 antibody LY 75 antibody Ly-75 antibody LY75 antibody LY75_HUMAN antibody Lymphocyte antigen 75 antibody Renal Cell Carcinoma (gp200) antibody |
| Product description | DEC-205 (LY75, lymphocyte antigen 75, GP200-MR6) is a 1,695 residue (mature form) multilectin receptor that belongs to the MMR (macrophage mannose receptor) family of multidomain molecules. MMR family molecules mediate membrane receptor targeting to endosomes or lysosomes rich in major histocompatibility complex class II (MHC II) products. Expressed in mature dendritic cells (DC), DEC-205 contains an extracellular N-terminal cysteine-rich domain, a fibronectin type II domain, ten C-type carbohydrate recognition domains, a single transmembrane region and a small cytoplasmic C-terminal domain (31 amino acids) containing a tyrosine at 1679. DEC-205 elicits either an agonistic or antagonistic effect on IL-4 function, which is demonstrated by the ability of DEC-205 to imitate IL-4-induced maturation of epithelium or to inhibit IL-4-induced proliferation of T cells, respectively. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHCIP |
| IHC:1:50-1:200 WB:1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | C-type lectin domain family 13 member B antibody CD 205 antibody CD205 antibody CD205 antigen antibody CLEC 13B antibody CLEC13B antibody DEC 205 antibody DEC-205 antibody DEC205 antibody gp200 antibody gp200 MR6 antibody gp200-MR6 antibody LY 75 antibody Ly-75 antibody LY75 antibody LY75_HUMAN antibody Lymphocyte antigen 75 antibody Renal Cell Carcinoma (gp200) antibody |
|---|---|
| Molecular Weight(MW) | 198 kDa |
| Cellular Localization | Membrane. |
Application
Fig1:Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-LY75 antibody. Counter stained with hematoxylin.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-LY75 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-LY75 antibody. Counter stained with hematoxylin.
Application
Fig4:Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-LY75 antibody. Counter stained with hematoxylin.| Positive Control | Human tonsil tissue, human colon cancer tissue, human kidney tissue, mouse colon tissue. |
|---|---|
| Application Notes | IHC:1:50-1:200 WB:1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
