Application
Fig1: Western blot analysis of Bcl-6 on NIH-3T3 cell lysate using anti-Bcl-6 antibody at 1/500 dilution.| Product Name | Bcl-6 [JB18-48] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | B Cell Lymphoma 6 Protein antibody B-cell CLL/lymphoma 6 antibody B-cell lymphoma 5 protein antibody B-cell lymphoma 6 protein transcript antibody BCL5 antibody BCL6A antibody cys-his2 zinc finger transcription factor antibody LAZ3 antibody lymphoma-associated zinc finger gene on chromosome 3 antibody Protein LAZ-3 antibody ZBTB27 antibody Zinc finger and BTB domain-containing protein 27 antibody Zinc Finger Protein 51 antibody zinc finger transcription factor BCL6S antibody ZNF51 antibody |
| Product description | Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and Th1/Th2 differentiation. Bcl-6 negatively regulates NFkB expression, thereby inhibiting NFkB-mediated cellular functions. HDAC- and silent information regulator (SIR)-2-dependent acet-ylation of Bcl-6 causes downregulation of activity by inhibiting the ability of Bcl-6 to recruit complexes containing histone deacetylases (HDACs). Bcl-6 is frequently deregulated in non-Hodgkin's B cell lymphomas. The human BCL6 gene has been shown to encode a protein of 706 amino acids. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WB |
| WB:1:1,000-1:5,000 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | B Cell Lymphoma 6 Protein antibody B-cell CLL/lymphoma 6 antibody B-cell lymphoma 5 protein antibody B-cell lymphoma 6 protein transcript antibody BCL5 antibody BCL6A antibody cys-his2 zinc finger transcription factor antibody LAZ3 antibody lymphoma-associated zinc finger gene on chromosome 3 antibody Protein LAZ-3 antibody ZBTB27 antibody Zinc finger and BTB domain-containing protein 27 antibody Zinc Finger Protein 51 antibody zinc finger transcription factor BCL6S antibody ZNF51 antibody |
|---|---|
| Molecular Weight(MW) | 79 kDa |
| Cellular Localization | Nucleus. |
Application
Fig1: Western blot analysis of Bcl-6 on NIH-3T3 cell lysate using anti-Bcl-6 antibody at 1/500 dilution.| Positive Control | SiHa, NIH-3T3. |
|---|---|
| Application Notes | WB:1:1,000-1:5,000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
