Application
Fig4: ICC staining SOCS2 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.Application
Fig4: ICC staining SOCS2 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.Application
Fig4: ICC staining SOCS2 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.Application
Fig4: ICC staining SOCS2 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.| Product Name | SOCS2 [JG36-86] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CIS 2 antibody CIS-2 antibody CIS2 antibody Cish 2 antibody Cish2 antibody Cytokine inducible SH2 protein 2 antibody Cytokine-inducible SH2 protein 2 antibody SOCS 2 antibody SOCS-2 antibody Socs2 antibody SOCS2_HUMAN antibody SSI 2 antibody SSI-2 antibody SSI2 antibody STAT induced STAT inhibitor 2 antibody STAT-induced STAT inhibitor 2 antibody STATI 2 antibody STATI2 antibody Suppressor of cytokine signaling 2 antibody |
| Product description | SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
| Immunogen | Recombinant protein within human SOCS2 1-150aa. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBICCIFIP |
| WB:1:500-1:2,000 ICC:1:50-1:200 IP:1:10-1:50 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CIS 2 antibody CIS-2 antibody CIS2 antibody Cish 2 antibody Cish2 antibody Cytokine inducible SH2 protein 2 antibody Cytokine-inducible SH2 protein 2 antibody SOCS 2 antibody SOCS-2 antibody Socs2 antibody SOCS2_HUMAN antibody SSI 2 antibody SSI-2 antibody SSI2 antibody STAT induced STAT inhibitor 2 antibody STAT-induced STAT inhibitor 2 antibody STATI 2 antibody STATI2 antibody Suppressor of cytokine signaling 2 antibody |
|---|---|
| Molecular Weight(MW) | 22 kDa |
| Cellular Localization | Cytosol. |
| SwissProt ID | O14508 |
|---|
Application
Fig4: ICC staining SOCS2 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig4: ICC staining SOCS2 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig4: ICC staining SOCS2 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig4: ICC staining SOCS2 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.| Positive Control | Human placenta tissue lysate, SH-SY-5Y, LOVO, PC-3M. |
|---|---|
| Application Notes | WB:1:500-1:2,000 ICC:1:50-1:200 IP:1:10-1:50 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
