Application
Fig1: Western blot analysis of Fibrinogen gamma chain on human plasma using anti-Fibrinogen gamma chain at 1/5,000 dilution.Application
Fig2: Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-Fibrinogen gamma chain antibody. Counter stained with hematoxylin.Application
Fig3: Flow cytometric analysis of HepG2 cells with Fibrinogen gamma chain antibody at 1/50 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.| Product Name | Fibrinogen gamma chain [JG37-18] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FGG antibody FIBG_HUMAN antibody Fibrinogen gamma chain antibody Fibrinogen gamma polypeptide antibody fibrinogen gamma-b chain antibody |
| Product description | Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways. |
| Immunogen | Recombinant protein corresponding to human Fibrinogen gamma 50-250aa. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHCFC |
| WB:1:5,000-1:10,000 IHC:1:50-1:200 FC:1:50-1:100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | FGG antibody FIBG_HUMAN antibody Fibrinogen gamma chain antibody Fibrinogen gamma polypeptide antibody fibrinogen gamma-b chain antibody |
|---|---|
| Molecular Weight(MW) | 52 kDa |
| Cellular Localization | Secreted. |
| SwissProt ID | P02679 |
|---|
Application
Fig1: Western blot analysis of Fibrinogen gamma chain on human plasma using anti-Fibrinogen gamma chain at 1/5,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-Fibrinogen gamma chain antibody. Counter stained with hematoxylin.
Application
Fig3: Flow cytometric analysis of HepG2 cells with Fibrinogen gamma chain antibody at 1/50 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.| Positive Control | Human plasma, human colon tissue, HepG2. |
|---|---|
| Application Notes | WB:1:5,000-1:10,000 IHC:1:50-1:200 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
