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SUN2 [JG39-52]

Catalog Number:OM638368
OM638368
Discount Price
OM638368-100ul
1~2 Week
100ul
OM638368-50ul
50ul
OM638368-20ul
20ul
1~2 Week
Product Profile
Product Name SUN2 [JG39-52]
Antibody Type Primary Antibodies
Antigen Alias FRIGG antibody KIAA0668 antibody nuclear envelope protein antibody Protein unc-84 homolog B antibody Rab5 interacting protein antibody RAB5IP antibody Sad1 and UNC84 domain containing 2 antibody Sad1 unc-84 domain protein 2 antibody Sad1 unc84 domain protein antibody Sad1/unc-84 protein-like 2 antibody Sad1/unc84 protein-like antibody SUN domain-containing protein 2 antibody UNC 84B antibody unc84 homolog B (C. elegans) antibody unc84 homolog B antibody unc84, C. elegans, homolog of, B antibody UNC84B antibody
Product description SUN2 (sad1/unc-84 protein-like 2), also known as UNC84B (unc-84 homolog B), FRIGG, KIAA0668 or RAB5IP, is a 717 amino acid single-pass membrane protein that contains one SUN domain and localizes to the membrane of both the nucleus and the endosome. Widely expressed in a variety of tissues, including lung, muscle and heart, SUN2 interacts with Rab 5A and may play a role in homotypic endosome fusion. The gene encoding SUN2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.
Immunogen Recombinant protein within human SUN2 aa 500-700.
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBIHCFCICCIF
WB:1:500-1:2,000
IHC:1:50-1:200
FC:1:50-1:100
ICC/IF:1:50-1:100
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Target Information
Alternative Names FRIGG antibody KIAA0668 antibody nuclear envelope protein antibody Protein unc-84 homolog B antibody Rab5 interacting protein antibody RAB5IP antibody Sad1 and UNC84 domain containing 2 antibody Sad1 unc-84 domain protein 2 antibody Sad1 unc84 domain protein antibody Sad1/unc-84 protein-like 2 antibody Sad1/unc84 protein-like antibody SUN domain-containing protein 2 antibody UNC 84B antibody unc84 homolog B (C. elegans) antibody unc84 homolog B antibody unc84
C. elegans
homolog of
B antibody UNC84B antibody
Molecular Weight(MW) 80 kDa
Cellular Localization Endosome. Nucleus inner membrane.
Database Links
SwissProt ID Q9UH99 Q8BJS4
Application

Application

Fig8: Flow cytometric analysis of SK-Br-3 cells with SUN2 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.

Application

Fig8: Flow cytometric analysis of SK-Br-3 cells with SUN2 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.

Application

Fig8: Flow cytometric analysis of SK-Br-3 cells with SUN2 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.

Application

Fig8: Flow cytometric analysis of SK-Br-3 cells with SUN2 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.

Application

Fig8: Flow cytometric analysis of SK-Br-3 cells with SUN2 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.

Application

Fig8: Flow cytometric analysis of SK-Br-3 cells with SUN2 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.

Application

Fig8: Flow cytometric analysis of SK-Br-3 cells with SUN2 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.

Application

Fig8: Flow cytometric analysis of SK-Br-3 cells with SUN2 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Positive Control Rat kidney tissue lysate, rat epididymis tissue, human tonsil tissue, human colon tissue, human prostate cancer tissue, mouse liver tissue, SK-Br-3.
Application Notes WB:1:500-1:2,000
IHC:1:50-1:200
FC:1:50-1:100
ICC/IF:1:50-1:100
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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