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JNK1

Catalog Number:OM638761
OM638761
Discount Price
OM638761-100ul
1~2 Week
100ul
OM638761-50ul
50ul
OM638761-20ul
20ul
1~2 Week
Product Profile
Product Name JNK1
Antibody Type Primary Antibodies
Antigen Alias AI849689 antibody c Jun N terminal kinase 1 antibody C-JUN kinase 1 antibody c-Jun N-terminal kinase 1 antibody EC 2.7.11.24 antibody JNK 1 antibody JNK antibody JNK-46 antibody JNK1A2 antibody JNK21B1/2 antibody MAP kinase 8 antibody MAPK 8 antibody mapk8 antibody Mitogen activated protein kinase 8 antibody Mitogen-activated protein kinase 8 antibody MK08_HUMAN antibody p54 gamma antibody Prkm8 antibody Protein kinase JNK1 antibody Protein kinase, mitogen-activated, 8 antibody SAPK 1 antibody SAPK gamma antibody SAPK1 antibody Stress-activated protein kinase 1 antibody Stress-activated protein kinase JNK1 antibody
Product description Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK8/JNK1. In turn, MAPK8/JNK1 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity.
Immunogen peptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBICCIHCFC
WB:1:1,000-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Species Reactivity HumanMouseRatZebra Fish
Concentration 1mg/ml
Target Information
Alternative Names AI849689 antibody c Jun N terminal kinase 1 antibody C-JUN kinase 1 antibody c-Jun N-terminal kinase 1 antibody EC 2.7.11.24 antibody JNK 1 antibody JNK antibody JNK-46 antibody JNK1A2 antibody JNK21B1/2 antibody MAP kinase 8 antibody MAPK 8 antibody mapk8 antibody Mitogen activated protein kinase 8 antibody Mitogen-activated protein kinase 8 antibody MK08_HUMAN antibody p54 gamma antibody Prkm8 antibody Protein kinase JNK1 antibody Protein kinase
mitogen-activated
8 antibody SAPK 1 antibody SAPK gamma antibody SAPK1 antibody Stress-activated protein kinase 1 antibody Stress-activated protein kinase JNK1 antibody
Molecular Weight(MW) ~48/54kDa
Cellular Localization Cytoplasm, nucleus
Database Links
SwissProt ID P45983
Application

Application

Fig1: Western blot analysis of JNK1 on different cell lysates using anti-JNK1 antibody at 1/1,000 dilution.Positive control:Lane 1: K562Lane 2: PC-12Lane 3: Hela

Application

Fig2: Western blot analysis of JNK1 on hybrid fish (crucian-carp) brain tissue lysate using anti-JNK1 antibody at 1/500 dilution.
Positive Control Hela, K562, PC12
Application Notes WB:1:1,000-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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