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AXL

Catalog Number:OM638819
OM638819
Discount Price
OM638819-100ul
1~2 Week
100ul
OM638819-50ul
50ul
OM638819-20ul
20ul
1~2 Week
Product Profile
Product Name AXL
Antibody Type Primary Antibodies
Antigen Alias Adhesion related kinase antibody AI323647 antibody Ark antibody Axl antibody AXL oncogene antibody AXL receptor tyrosine kinase antibody AXL transforming gene antibody AXL transforming sequence/gene antibody EC 2.7.10.1 antibody JTK11 antibody Oncogene AXL antibody Tyro7 antibody Tyrosine protein kinase receptor UFO antibody Tyrosine-protein kinase receptor UFO antibody UFO antibody UFO_HUMAN antibody
Product description The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse (also designated Tyro3, Sky, Brt, Dtk, Etk2 and Tif), Axl (also designated UFO or ARK) and Mer (also designated Nyk or Eyk). Rse is expressed Preferentially in the adult brain with lower expression in other tissues. Axl is found at highest levels in heart and skeletal muscle. Mer has been identified as a tyrosine kinase is involved in the development of glioblastomas. It is expressed at highest levels in ovary, prostate , Lung and kidney. Gas6, a growth arrest specific gene, and the related anticoagulation factor Protein S, have been identified as ligands for the UFO family of receptors.
Immunogen Recombinant protein within human AXL 1-200 aa.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBICC
WB:1:500
ICC:1:50-1:200
Species Reactivity HumanMouse
Concentration 2mg/ml
Target Information
Alternative Names Adhesion related kinase antibody AI323647 antibody Ark antibody Axl antibody AXL oncogene antibody AXL receptor tyrosine kinase antibody AXL transforming gene antibody AXL transforming sequence/gene antibody EC 2.7.10.1 antibody JTK11 antibody Oncogene AXL antibody Tyro7 antibody Tyrosine protein kinase receptor UFO antibody Tyrosine-protein kinase receptor UFO antibody UFO antibody UFO_HUMAN antibody
Molecular Weight(MW) 98 kDa(Predicted band)
Cellular Localization Membrane.
Database Links
SwissProt ID P30530 Q00993
Application

Application

Fig1: Western blot analysis of AXL on different lysates using anti-AXL antibody at 1/100 dilution.Positive control:Lane1: Mouse kidney tissueLane2: CRC

Application

Fig2: Western blot analysis of AXL on human AXL recombinant protein using anti-AXL antibody at 1/1,000 dilution.

Application

Fig3: ICC staining AXL in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig4: ICC staining AXL in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig5: ICC staining AXL in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Positive Control Mouse kidney tissue lysate, CRC cell lysate, human AXL recombinant protein lysate, Hela, LOVO, MCF-7.
Application Notes WB:1:500
ICC:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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