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Tet1

Catalog Number:OM638849
OM638849
Discount Price
OM638849-100ul
1~2 Week
100ul
OM638849-50ul
50ul
OM638849-20ul
20ul
1~2 Week
Product Profile
Product Name Tet1
Antibody Type Primary Antibodies
Antigen Alias bA119F7.1 antibody CXXC 6 antibody CXXC finger 6 antibody CXXC type zinc finger protein 6 antibody CXXC zinc finger 6 antibody CXXC-type zinc finger protein 6 antibody CXXC6 antibody KIAA1676 antibody LCX antibody Leukemia associated protein with a CXXC domain antibody Leukemia-associated protein with a CXXC domain antibody Methylcytosine dioxygenase TET1 antibody Ten eleven translocation 1 antibody Ten eleven translocation 1 gene protein antibody Ten eleven translocation 1 gene protein homolog antibody Ten-eleven translocation 1 gene protein antibody Tet 1 antibody Tet methylcytosine dioxygenase 1 antibody Tet oncogene 1 antibody TET1 antibody TET1_HUMAN antibody
Product description TET1 (tet oncogene 1), also known as LCX or CXXC6, is a 2,136 amino acid protein that localizes to the nucleus and contains one CXXC-type zinc finger. Expressed in adult ovary, thymus and skeletal muscle and also present in fetal lung, heart and brain, TET1 is thought to play a role in the development of fetal organs and may also be involvement in the pathoegenesis and metastasis of acute myeloid leukemia (AML). The gene encoding TET1 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
Immunogen Synthetic peptide (KLH-coupled) within human TET1 820-900 aa.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCFCICC
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Target Information
Alternative Names bA119F7.1 antibody CXXC 6 antibody CXXC finger 6 antibody CXXC type zinc finger protein 6 antibody CXXC zinc finger 6 antibody CXXC-type zinc finger protein 6 antibody CXXC6 antibody KIAA1676 antibody LCX antibody Leukemia associated protein with a CXXC domain antibody Leukemia-associated protein with a CXXC domain antibody Methylcytosine dioxygenase TET1 antibody Ten eleven translocation 1 antibody Ten eleven translocation 1 gene protein antibody Ten eleven translocation 1 gene protein homolog antibody Ten-eleven translocation 1 gene protein antibody Tet 1 antibody Tet methylcytosine dioxygenase 1 antibody Tet oncogene 1 antibody TET1 antibody TET1_HUMAN antibody
Molecular Weight(MW) 235kDa
Cellular Localization Nucleus
Database Links
SwissProt ID Q8NFU7 Q3URK3
Application

Application

Fig1: Immunocytochemical staining of SH-SY-5Y cells using anti-TET1 rabbit polyclonal antibody.

Application

Fig2: Immunohistochemical analysis of paraffin- embedded mouse brain tissue using anti-TET1 rabbit polyclonal antibody.

Application

Fig3: Flow cytometric analysis of SH-SY-5Y cells with TET1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.
Positive Control SH-SY-5Y, mouse brain tissue.
Application Notes ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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