Application
Fig1: Western blot analysis of 5-lipoxygenase on Hela (1) and Jurkat (2) lysates using anti-5-lipoxygenase antibody at 1/1,000 dilution.| Product Name | 5 Lipoxygenase |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 5 LO antibody 5 LOX antibody 5-lipoxygenase antibody 5-LO antibody 5-LOX antibody 5LOX antibody 5LPG antibody ALOX 5 antibody Alox5 antibody Arachidonate 5 lipoxygenase antibody Arachidonate 5-lipoxygenase antibody arachidonic 5-lipoxygenase alpha-10 isoform antibody arachidonic 5-lipoxygenase delta-10-13 isoform antibody arachidonic 5-lipoxygenase delta-13 isoform antibody arachidonic 5-lipoxygenase delta-p10 isoform antibody Arachidonic acid 5 lipoxygenase antibody Leukotriene A4 synthase antibody LOG 5 antibody LOG5 antibody LOX5_HUMAN antibody MGC163204 antibody |
| Product description | 5-lipoxygenase (5-LO) is expressed primarily in polymorphonuclear leukocytes, macrophages, and mast cells. 5-LO performs the first two catalytic reactions in the biosynthesis of leukotrienes, lipid metabolites that induce contractions of airway smooth muscle and increase vascular permeability during anaphylaxis. The cellular localization of 5-LO varies between cell types. In activated blood polymorphonuclear leukocytes 5-LO undergoes calcium dependent translocation from the cytosol to the nuclear envelope. In alveolar macrophages, the majority of 5-LO is localized in the nucleus and, upon activation of these cells, intranuclear 5-LO binds to the nuclear membrane. This intracellular shuttling of 5-LO is dependent on the association with various signaling molecules, phosphorylation and the presence of a distinct |
| Immunogen | Peptide. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:1,000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | 5 LO antibody 5 LOX antibody 5-lipoxygenase antibody 5-LO antibody 5-LOX antibody 5LOX antibody 5LPG antibody ALOX 5 antibody Alox5 antibody Arachidonate 5 lipoxygenase antibody Arachidonate 5-lipoxygenase antibody arachidonic 5-lipoxygenase alpha-10 isoform antibody arachidonic 5-lipoxygenase delta-10-13 isoform antibody arachidonic 5-lipoxygenase delta-13 isoform antibody arachidonic 5-lipoxygenase delta-p10 isoform antibody Arachidonic acid 5 lipoxygenase antibody Leukotriene A4 synthase antibody LOG 5 antibody LOG5 antibody LOX5_HUMAN antibody MGC163204 antibody |
|---|---|
| Molecular Weight(MW) | 78 kDa |
| Cellular Localization | Cytoplasm. Nucleus matrix. Nucleus membrane. |
Application
Fig1: Western blot analysis of 5-lipoxygenase on Hela (1) and Jurkat (2) lysates using anti-5-lipoxygenase antibody at 1/1,000 dilution.| Positive Control | A549, HUVEC, rat prostate tissue, human tonsil tissue, mouse pancreas tissue. |
|---|---|
| Application Notes | WB:1:500-1:1,000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
