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WDR5

Catalog Number:OM638924
OM638924
Discount Price
OM638924-100ul
1~2 Week
100ul
OM638924-50ul
50ul
OM638924-20ul
20ul
1~2 Week
Product Profile
Product Name WDR5
Antibody Type Primary Antibodies
Antigen Alias 2410008O07Rik antibody AA408785 antibody AA960360 antibody BIG 3 antibody Big antibody BIG3 antibody BMP2 induced 3 kb gene protein antibody BMP2 induced gene, 3-KB antibody BMP2-induced 3-kb gene protein antibody MGC114572 antibody OTTHUMP00000162494 antibody SWD 3 antibody SWD3 antibody SWD3 Set1c WD40 repeat protein homolog antibody WD repeat containing protein 5 antibody WD repeat domain 5 antibody WD repeat protein 5 antibody WD repeat-containing protein 5 antibody WD repeat-containing protein BIG-3 antibody WDR 5 antibody Wdr5 antibody WDR5_HUMAN antibody
Product description WD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.
Immunogen Recombinant protein
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBICCFC
WB:1:500-1:1,000
ICC:1:50-1:200
FC:1:50-1:100
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names 2410008O07Rik antibody AA408785 antibody AA960360 antibody BIG 3 antibody Big antibody BIG3 antibody BMP2 induced 3 kb gene protein antibody BMP2 induced gene
3-KB antibody BMP2-induced 3-kb gene protein antibody MGC114572 antibody OTTHUMP00000162494 antibody SWD 3 antibody SWD3 antibody SWD3 Set1c WD40 repeat protein homolog antibody WD repeat containing protein 5 antibody WD repeat domain 5 antibody WD repeat protein 5 antibody WD repeat-containing protein 5 antibody WD repeat-containing protein BIG-3 antibody WDR 5 antibody Wdr5 antibody WDR5_HUMAN antibody
Molecular Weight(MW) 36 kDa, additional band 70 kDa.
Cellular Localization Nucleus.
Database Links
SwissProt ID P61964
Application

Application

Fig5: Flow cytometric analysis of MCF-7 cells with WDR5 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.

Application

Fig5: Flow cytometric analysis of MCF-7 cells with WDR5 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.

Application

Fig5: Flow cytometric analysis of MCF-7 cells with WDR5 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.

Application

Fig5: Flow cytometric analysis of MCF-7 cells with WDR5 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.

Application

Fig5: Flow cytometric analysis of MCF-7 cells with WDR5 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
Positive Control Hela, MCF-7, PC-3M.
Application Notes WB:1:500-1:1,000
ICC:1:50-1:200
FC:1:50-1:100
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
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