Application
Fig1: Western blot analysis of Aldh1A1 on different tissue lysate using anti-Aldh1A1 antibody at 1/1,000 dilution. Positive control：Lane1: Mouse liverLane2: Human liverApplication
Fig2: ICC staining Aldh1A1 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.Application
Fig3: ICC staining Aldh1A1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.Application
Fig4: Immunohistochemical analysis of paraffin-embedded rat epididymis tissue using anti-Aldh1A1 antibody. Counter stained with hematoxylin.Application
Fig5: Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-Aldh1A1 antibody. Counter stained with hematoxylin.| Product Name | Aldh1A1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Acetaldehyde dehydrogenase 1 antibody AHD2 antibody AL1A1_HUMAN antibody ALDC antibody Aldehyde dehydrogenase 1 family member A1 antibody Aldehyde dehydrogenase 1 soluble antibody Aldehyde dehydrogenase 1A1 antibody Aldehyde dehydrogenase antibody Aldehyde dehydrogenase cytosolic antibody Aldehyde dehydrogenase family 1 member A1 antibody Aldehyde dehydrogenase liver cytosolic antibody ALDH 1 antibody ALDH 1A1 antibody ALDH class 1 antibody ALDH, liver cytosolic antibody ALDH-E1 antibody ALDH1 A1 antibody ALDH1 antibody ALDH11 antibody ALDH1A1 antibody ALHDII antibody cytosolic antibody epididymis luminal protein 12 antibody epididymis luminal protein 9 antibody epididymis secretory sperm binding protein Li 53e antibody HEL-S-53e antibody MGC2318 antibody PUMB1 antibody RALDH 1 antibody RalDH1 antibody Retinal dehydrogenase 1 antibody |
| Product description | Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during the detoxification of alcohol-derived acetaldehyde; metabolism of corticosteroids, biogenic amines and neurotransmitters; and lipid peroxidation. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1), aldehyde dehydrogenase family 1 member A1, aldehyde dehydrogenase cytosolic, ALDHII, ALDH-E1 or ALDH E1, is a retinal dehydrogenase that participates in the biosynthesis of retinoic acid (RA). There are two major liver isoforms of ALDH1 that can localize to cytosolic or mitochondrial space. The ALDH1A2 (RALDH2, RALDH2-T) gene produces three different transcripts and also catalyzes the synthesis of RA from retinaldehyde. ALDH1A3 (ALDH6, RALDH3, ALDH1A6) is a 37 kb gene that consists of 13 exons and produces a major transcript of approximately 3.5 kb most abundant in salivary gland, stomach and kidney. ALDH3A1 (stomach type, ALDH3, ALDHIII) forms a cytoplasmic homodimer that preferentially oxidizes aromatic aldehyde substrates. ALDH genes upregulate as a part of the oxidative stress response, and appear to be abundant in certain tumors that have an accelerated metabolism toward chemotherapy agents. |
| Immunogen | Recombinant protein. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBICCIHC |
| WB:1:500~1:2000 ICC:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | Acetaldehyde dehydrogenase 1 antibody
AHD2 antibody
AL1A1_HUMAN antibody
ALDC antibody
Aldehyde dehydrogenase 1 family member A1 antibody
Aldehyde dehydrogenase 1 soluble antibody
Aldehyde dehydrogenase 1A1 antibody
Aldehyde dehydrogenase antibody
Aldehyde dehydrogenase cytosolic antibody
Aldehyde dehydrogenase family 1 member A1 antibody
Aldehyde dehydrogenase liver cytosolic antibody
ALDH 1 antibody
ALDH 1A1 antibody
ALDH class 1 antibody
ALDH liver cytosolic antibody ALDH-E1 antibody ALDH1 A1 antibody ALDH1 antibody ALDH11 antibody ALDH1A1 antibody ALHDII antibody cytosolic antibody epididymis luminal protein 12 antibody epididymis luminal protein 9 antibody epididymis secretory sperm binding protein Li 53e antibody HEL-S-53e antibody MGC2318 antibody PUMB1 antibody RALDH 1 antibody RalDH1 antibody Retinal dehydrogenase 1 antibody |
|---|---|
| Molecular Weight(MW) | 55 kDa |
| Cellular Localization | Cytoplasm. |
Application
Fig1: Western blot analysis of Aldh1A1 on different tissue lysate using anti-Aldh1A1 antibody at 1/1,000 dilution. Positive control：Lane1: Mouse liverLane2: Human liver
Application
Fig2: ICC staining Aldh1A1 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: ICC staining Aldh1A1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded rat epididymis tissue using anti-Aldh1A1 antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-Aldh1A1 antibody. Counter stained with hematoxylin.| Positive Control | Mouse liver tissue lysate, human liver tissue lysate, A549, HepG2, rat epididymis tissue, human pancreas tissue. |
|---|---|
| Application Notes | WB:1:500~1:2000 ICC:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
