Application
Fig1: Western blot analysis on human spleen lysate using anti-Integrin beta 3Application
Fig2： Immunohistochemical analysis of paraffin-embedded human tonsil using anti-Integrin beta 3.| Product Name | Integrin beta 3 [1J8] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BDPLT16 antibody BDPLT2 antibody CD 61 antibody CD61 antibody CD61 antigen antibody GP3A antibody GPIIIa antibody GT antibody HPA 1 antibody HPA 4 antibody Integrin beta 3 (platelet glycoprotein IIIa antigen CD61) antibody Integrin beta chain beta 3 antibody Integrin beta-3 antibody ITB3_HUMAN antibody ITG B3 antibody ITGB 3 antibody ITGB3 antibody NAIT antibody Platelet fibrinogen receptor beta subunit antibody Platelet fibrinogen receptor, beta subunit antibody Platelet glycoprotein IIIa antibody Platelet glycoprotein IIIa precursor antibody Platelet membrane glycoprotein IIIa antibody PTP antibody |
| Product description | Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis |
| Immunogen | peptide |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1,000 IHC:1:100 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | BDPLT16 antibody
BDPLT2 antibody
CD 61 antibody
CD61 antibody
CD61 antigen antibody
GP3A antibody
GPIIIa antibody
GT antibody
HPA 1 antibody
HPA 4 antibody
Integrin beta 3 (platelet glycoprotein IIIa antigen CD61) antibody
Integrin beta chain beta 3 antibody
Integrin beta-3 antibody
ITB3_HUMAN antibody
ITG B3 antibody
ITGB 3 antibody
ITGB3 antibody
NAIT antibody
Platelet fibrinogen receptor beta subunit antibody
Platelet fibrinogen receptor beta subunit antibody Platelet glycoprotein IIIa antibody Platelet glycoprotein IIIa precursor antibody Platelet membrane glycoprotein IIIa antibody PTP antibody |
|---|---|
| Molecular Weight(MW) | 87kDa |
| Cellular Localization | Cell membrane, Cell projection, Cell junction |
| SwissProt ID | P05106 |
|---|
Application
Fig1: Western blot analysis on human spleen lysate using anti-Integrin beta 3
Application
Fig2： Immunohistochemical analysis of paraffin-embedded human tonsil using anti-Integrin beta 3.| Positive Control | Human spleen, human tonsil |
|---|---|
| Application Notes | WB:1:1,000 IHC:1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
