Application
Fig1: Western blot analysis on C6 cell lysate using anti-Pan-Cadherin.Application
Fig2： Immunohistochemical staining of paraffin-embedded human cervical carcinoma tissue using anti-Pan-Cadherin.| Product Name | Pan Cadherin |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Cadherin antibody CDH3 antibody CDHP antibody 7B4 antigen antibody Cadherin-1 antibody Cadherin-2 antibody Cadherin-3 antibody Cadherin-4 antibody Cadherin-5 antibody CAM 120/80 antibody CD144 antibody CD324 antibody CD325 antibody Cdh4 antibody CDH5 antibody CDHE antibody CDHN antibody E-cadherin antibody Epithelial cadherin antibody N-cadherin antibody NCAD antibody Neural cadherin antibody P-cadherin antibody Placental cadherin antibody UVO antibody Uvomorulin antibody Vascular endothelial cadherin antibody |
| Product description | The cadherins are a large family of cell adhesion molecules involved in calcium-dependent recognition and adhesion events (1). Synaptic remodeling has been postulated as a mechanism underlying synaptic plasticity, and cadherin adhesion molecules are thought to be a regulator of such a process. Findings suggest that cadherin regulates dendritic spine morphogenesis and related synaptic functions, presumably cooperating with cadherin-independent adhesive mechanisms to maintain spine-axon contacts (2). Human retinoblastoma and normal retinal tissue the type of cadherin, its relationship with cytoplasmic catenins, and its participation in invasion has been examined. Retinoblastoma cells, in contrast with normal retina, express an cadherin-2/catenin complex that is irregularly distributed and weakly linked to the cytoskeleton. In retinoblastoma, this complex acts as an invasion promoter (3). |
| Immunogen | peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBICCIHCFCIP |
| WB:1:1,000 ICC:1:100 IHC:1:100 IP:1:40 FC:1:30 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | Cadherin antibody CDH3 antibody CDHP antibody 7B4 antigen antibody Cadherin-1 antibody Cadherin-2 antibody Cadherin-3 antibody Cadherin-4 antibody Cadherin-5 antibody CAM 120/80 antibody CD144 antibody CD324 antibody CD325 antibody Cdh4 antibody CDH5 antibody CDHE antibody CDHN antibody E-cadherin antibody Epithelial cadherin antibody N-cadherin antibody NCAD antibody Neural cadherin antibody P-cadherin antibody Placental cadherin antibody UVO antibody Uvomorulin antibody Vascular endothelial cadherin antibody |
|---|---|
| Molecular Weight(MW) | 140kDa |
| Cellular Localization | Cytoplasm, Cell junction |
| SwissProt ID | P19022 |
|---|
Application
Fig1: Western blot analysis on C6 cell lysate using anti-Pan-Cadherin.
Application
Fig2： Immunohistochemical staining of paraffin-embedded human cervical carcinoma tissue using anti-Pan-Cadherin.| Positive Control | C6, human cervical carcinoma tissue. |
|---|---|
| Application Notes | WB:1:1,000 ICC:1:100 IHC:1:100 IP:1:40 FC:1:30 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 ℃. Stable for 12 months from date of receipt |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
