| Product Name | GLP1R |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GLP 1 R antibody GLP 1 receptor antibody GLP 1R antibody GLP antibody GLP-1 receptor antibody GLP-1-R antibody GLP-1R antibody GLP1R antibody GLP1R_HUMAN antibody Glucagon like peptide 1 receptor antibody Glucagon-like peptide 1 receptor antibody MGC138331 antibody OTTHUMP00000016340 antibody |
| Product description | Glucagon, a pancreatic hormone, functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior. Both Glucagon and GLP-1 function through their specific binding to the Glucagon receptor or GLP-1R, respectively. The Glucagon receptor shows expression in liver, kidney and adipose tissue. GLP-1R expression primarily localizes to areas of the hypothalamus involved in feeding behavior. Both receptors and their ligands serve as potential targets for the therapeutic treatment of diabetes. |
| Immunogen | Amino acids 9 1 - 145 mapping within an N-terminal extracellular domain of GLP-1R of human origin. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIF |
| WB:1:100-1:1,000 IP:1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) IF:1:50-500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | GLP 1 R antibody GLP 1 receptor antibody GLP 1R antibody GLP antibody GLP-1 receptor antibody GLP-1-R antibody GLP-1R antibody GLP1R antibody GLP1R_HUMAN antibody Glucagon like peptide 1 receptor antibody Glucagon-like peptide 1 receptor antibody MGC138331 antibody OTTHUMP00000016340 antibody |
|---|---|
| Molecular Weight(MW) | 56 kDa |
| Cellular Localization | Cell membrane |
| SwissProt ID | P43220 |
|---|
| Application Notes | WB:1:100-1:1,000 IP:1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) IF:1:50-500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
