Purified recombinant fragment of human CD55 (AA: 238-357) expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Host Species
Mouse
Tested Applications
FCWB
WB:1:500 - 1:2000 FC:1:200 - 1:400
Species Reactivity
Human
Purification
Affinity purified
Target Information
Gene Symbol
CD55
Gene Synonyms
CR TC DAF CROM CHAPLE
Gene Full Name
CD55 molecule (Cromer blood group)
Gene Summary
This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins. [provided by RefSeq, Jul 2014]
Alternative Names
CR TC DAF CROM
Molecular Weight(MW)
41.4kDa
Cellular Localization
Cell membrane,Membrane,Secreted.
Application
WB
Western blot analysis using CD55 mouse mAb against Raji (1) and K562 (2) cell lysate.
FC
Flow cytometric analysis of K562 cells using CD55 mouse mAb (green) and negative control (red).
Application Notes
WB:1:500 - 1:2000 FC:1:200 - 1:400
Additional Information
Storage Instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.