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AFP
Catalog Number:OM641241
OM641241
Discount Price
OM641241-100μl
1~2 Week
100μl
1~2 Week
Product Profile
Product Name AFP
Antibody Type Primary Antibodies
Immunogen Purified recombinant fragment of human AFP expressed in E. Coli.
Key Feature
Clonality Monoclonal
Isotype IgG2b
Host Species Mouse
Tested Applications ICC/IFWB
WB:1:250~1:1000
ICC/IF:1:100~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity Human
Purification Affinity purified
Target Information
Gene Symbol AFP
Gene Synonyms AFPD
FETA
HPAFP
Gene Full Name alpha fetoprotein
Gene Summary This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Oct 2019]
Alternative Names alpha-fetoprotein
FETA
HPAFP
Molecular Weight(MW) 69kDa
Database Links
Entrez Gene 174
Application

Application

Figure 1: Western blot analysis using AFP mouse mAb against HepG2 (1) and SMMC-7721 (2) cell lysate.
Application Notes WB:1:250~1:1000
ICC/IF:1:100~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Ascitic fluid containing 0.03% sodium azide.
Storage Instructions 4℃; -20℃ for long term storage
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