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Anti-E2F1 antibody-HRP

Catalog Number:OM641880-HRP
Human;Mouse;Rat
WB;IHC
OM641880-HRP
Discount Price
OM641880-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-E2F1 antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol E2F1
Gene Synonyms RBP3
E2F-1
RBAP1
RBBP3
Gene Full Name E2F transcription factor 1
Gene Summary The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 47 KDa
Source Rabbit
Cellular Localization Nucleus
Database Links
SwissProt ID Q01094
Application

WB

Western blot analysis using E2F1 antibody against A549 (1), CaCo-2 (2) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using E2F1 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast tissues using E2F1 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human colon cancer tissues using E2F1 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using E2F1 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using E2F1 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using E2F1 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using E2F1 antibody with DAB staining.

WB

Western blot analysis using Catenin gamma antibody against Mouse testes(1),Mouse heart(2),Mouse stomach(3),Rat stomach(4) tissue.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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