| Product Name | Anti-Hsp22 antibody-DBCO |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | DBCO |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | HSPB8 |
|---|---|
| Gene Synonyms | CMT2L Cryac D5Ucla4 DHMN2 E2IG1 H11 H11K HMN2 HMN2A HMND2 HSP20-like HSP22 HSPB8-N1 HSPB8-N2 MFM13 |
| Gene Full Name | heat shock protein family B (small) member 8 |
| Gene Summary | The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. |
| Alternative Names | alpha-crystallin C chain Alternatively spliced isoform of human HSPB8 protein crystallin alpha C DHMN 2 E2-induced gene 1 protein heat shock 22kDa protein 8 heat shock 27kDa protein 8 Heat shock protein heat shock protein 20-like protein heat shock protein 8 heat shock protein B8 heat shock protein family B member 8 HMN 2 HSB8 HSP HSP-20-like protein HSP22 HSPB 8 HSPB8 OTTHUMP00000239768 protein kinase H11 small stress protein-like protein HSP22 |
| Molecular Weight(MW) | 22kDa（observed：25kDa) |
| Cellular Localization | Cytoplasm, Nucleus |
| SwissProt ID | Q9UJY1 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
