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PTP epsilon (PTPRE) Mouse Monoclonal Antibody

Catalog Number:OM643666
OM643666
Discount Price
OM643666-100ul
2~3 Week
100ul
OM643666-50ul
50ul
2~3 Week
Product Profile
Product Name PTP epsilon (PTPRE) Mouse Monoclonal Antibody
Antibody Type Primary Antibodies
Immunogen Full length human recombinant protein of human PTPRE (NP_006495) produced in HEK293T cell.
Key Feature
Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications ICC/IFIHCWB
WB:1:2000
IHC:1:50
ICC:1:100
Species Reactivity HumanMouseRat
Concentration 0.7mg/ml
Purification Affinity purified
Target Information
Gene Symbol PTPRE
Gene Synonyms PTPE
HPTPE
R-PTP-EPSILON
Gene Full Name protein tyrosine phosphatase receptor type E
Gene Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels. [provided by RefSeq, Oct 2015]
Alternative Names HPTPE
PTPE
R-PTP-EPSILON
Molecular Weight(MW) 80kDa
Source Store at -20°C as received.Stable for 12 months from date of receipt.
Cellular Localization Cell membrane,Cytoplasm.
Application

WB

Western blot analysis of extracts (10ug) from 3 different cell lines by using anti-PTPRE monoclonal antibody at 1:200 dilution.

IHC

Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-PTPRE mouse monoclonal antibody. (heat-induced epitope retrieval by 1mM EDTA in 10mM Tris, pH8.5, 120°C for 3min)

ICC/IF

Immunofluorescent staining of HT29 cells using anti-PTPRE mouse monoclonal antibody.
Application Notes WB:1:2000
IHC:1:50
ICC:1:100
Additional Information
Form Liquid
Storage Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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