WB
Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night.| Product Name | FILA2 Rabbit pAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthesized peptide derived from human FILA2 AA range: 402-452 |
| Clonality | polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FLG2 |
|---|---|
| Gene Synonyms | IFPS PSS6 |
| Gene Full Name | filaggrin 2 |
| Gene Summary | The filaggrin-like protein encoded by this gene is upregulated by calcium, proteolyzed by calpain 1, and is involved in epithelial homeostasis. The encoded protein is required for proper cornification in skin, with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact, in addition to providing a physical barrier, C-terminal fragments of this protein display antimicrobial activity against P. aeruginosa and E. coli. [provided by RefSeq, Jul 2020] |
| Molecular Weight(MW) | 263kDa |
| Cellular Localization | Cytoplasm . Cytoplasmic granule . |
WB
Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night.| Application Notes | WB:1:500-1:2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Storage Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
Data sheet for OM643885