A synthesized peptide derived from human Serum Amyloid A
Key Feature
Clonality
monoclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCWB
WB:1:500-1:2000 IHC:1:50-1:200
Species Reactivity
Human
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
SAA1
Gene Synonyms
SAA PIG4 SAA2 TP53I4
Gene Full Name
serum amyloid A1
Gene Summary
This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Finally, antimicrobial activity against S. aureus and E. coli resides in the N-terminal portion of the mature protein. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11. [provided by RefSeq, Jul 2020]
Molecular Weight(MW)
12kDa
Cellular Localization
Secreted.
Application
WB
Western blot analysis of Serum Amyloid A expression in human plasma lysate.
IHC
Immunohistochemical analysis of paraffin-embedded human liver cancer, using Serum Amyloid A Antibody.
Application Notes
WB:1:500-1:2000 IHC:1:50-1:200
Additional Information
Form
Liquid
Storage Instructions
12 months from date of receipt, -20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
Storage Buffer
500ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.