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ABCA1 Mouse Monoclonal AntibodyAntibody
Catalog Number:OM644069
OM644069
Discount Price
OM644069-100ul
100ul
Product Profile
Product Name ABCA1 Mouse Monoclonal AntibodyAntibody
Antibody Type Primary Antibodies
Immunogen 50kDa N-terminal extracellular loop of ABCA1
Key Feature
Clonality monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications FCIHCWB
WB:1:2000
IHC:1:400
FC:1ug per million cells
Species Reactivity HumanMonkeyRat
Purification Protein G
Target Information
Gene Symbol ABCA1
Gene Synonyms TGD
ABC1
CERP
ABC-1
HDLDT1
HPALP1
HDLCQTL13
Gene Full Name ATP binding cassette subfamily A member 1
Gene Summary The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency. [provided by RefSeq, Sep 2019]
Molecular Weight(MW) 254kDa
Cellular Localization Cell membrane,Endosome.
Application

WB

Western Blot: ABCA1 Antibody Detection of ABCA1 in wildtype liver tissue (in RIPA) Lane 1: KO mouse liver tissue. Lane 2: WT mouse liver tissue.

IHC

ABCA1 Antibody - Analysis of ABCA1 in human renal cancer using DAB with hematoxylin counterstain.

FC

ABCA1 Antibody - Staining of 1 x 10^6 CHO (A) and HEK-293 (B) cells using ABCA1 antibody (dark blue). Isotype control shown in orange. An antibody concentration of 1 ug/1x10^6 cells was used.
Application Notes WB:1:2000
IHC:1:400
FC:1ug per million cells
Additional Information
Form Liquid
Storage Instructions Store at -20°C as received. Stable for 12 months from date of receipt.
Storage Buffer PBS containing protease inhibitors and Sodium Azide.
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