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Axl Rabbit mAb
Catalog Number:OM644114
OM644114
Discount Price
OM644114-100ul
100ul
OM644114-50ul
50ul
OM644114-20ul
20ul
Product Profile
Product Name Axl Rabbit mAb
Antibody Type Primary Antibodies
Key Feature
Clonality monoclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCWB
WB:1:1000-1:5000
IHC:1:200-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol AXL
Gene Synonyms ARK
UFO
AXL3
JTK11
Tyro7
Gene Full Name AXL receptor tyrosine kinase
Gene Summary The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus. [provided by RefSeq, Sep 2021]
Molecular Weight(MW) 98kD (Calculated),138kD (Observed).
Cellular Localization Cell membrane, Single-pass type I membrane protein.
Application

WB

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Axl antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: Rat brain Lane 2: Du145 Lane 3: C2C12.

IHC

Mouse prostate was stained with anti-Axl rabbit antibody.
Application Notes WB:1:1000-1:5000
IHC:1:200-1:1000
Additional Information
Form Liquid
Storage Instructions -15°C to -25°C/1 year(Do not lower than -25°C)
Storage Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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