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CD3 Rabbit mAb
Catalog Number:OM644238
OM644238
Discount Price
OM644238-100ul
100ul
OM644238-50ul
50ul
OM644238-20ul
20ul
Product Profile
Product Name CD3 Rabbit mAb
Antibody Type Primary Antibodies
Key Feature
Clonality monoclonal
Isotype IgG
Host Species Rabbit
Tested Applications ICC/IFIF-PIHCWB
WB:1:1000-1:5000
IHC:1:200-1:1000
ICC/IF:1:200-1:1000
IF-P:1:200-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol CD3E
Gene Synonyms T3E
TCRE
IMD18
CD3epsilon
Gene Full Name CD3 epsilon subunit of T-cell receptor complex
Gene Summary The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 23kDa
Cellular Localization Membranous.
Application

WB

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-CD3 antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: Jurkat, Lane 2: EL-4-B5, Lane 3: Rat thymus.

IHC

Rat spleen was stained with anti-CD3 rabbit antibody.

IHC

Human tonsil was stained with anti-CD3 rabbit antibody.

IHC

Mouse spleen was stained with anti-CD3 rabbit antibody.

ICC/IF

Immunofluorescence analysis of HEK293. Picture A: CD3 antibody (red). Picture B: DAPI (blue). Picture C: Merge of A+B.

IF-P

Rat spleen was stained with anti-CD3 rabbit antibody.

IF-P

Mouse spleen was stained with anti-CD3 rabbit antibody.
Application Notes WB:1:1000-1:5000
IHC:1:200-1:1000
ICC/IF:1:200-1:1000
IF-P:1:200-1:1000
Additional Information
Form Liquid
Storage Instructions -15°C to -25°C/1 year(Do not lower than -25°C)
Storage Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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