WB
Western blot analysis of ANO1 expression in human skeletal muscle tissue extract (A) and RT-4 whole cell lysate (B).WB
Western blot analysis of ANO1 expression in extracts of human skeletal muscle (A) and human liver tissues(B).IHC
Immunoperoxidase staining of human gallbladder tissue fixed in formalin and embedded in paraffin reveals staining of glandular cell membrane and cytoplasm.| Product Name | Mouse Monoclonal antibody to ANO1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | raised against amino acids 182-222 mapping within an internal region of TMEM16A of human origin. |
| Clonality | monoclonal |
|---|---|
| Isotype | IgG2b,k |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| WB:1:100-1:1000 IHC:1:100-1:1000 |
|
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ANO1 |
|---|---|
| Gene Synonyms | DOG1 INDMS MYMY7 TAOS2 ORAOV2 TMEM16A |
| Gene Full Name | anoctamin 1 |
| Gene Summary | Enables identical protein binding activity; iodide transmembrane transporter activity; and ligand-gated monoatomic ion channel activity. Involved in several processes, including monoatomic anion transport; mucus secretion; and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Located in apical plasma membrane and nucleoplasm. Implicated in Moyamoya disease. [provided by Alliance of Genome Resources, Jul 2025] |
| Molecular Weight(MW) | 88 kDa |
| Cellular Localization | cell membrane and cytoplasm. |
WB
Western blot analysis of ANO1 expression in human skeletal muscle tissue extract (A) and RT-4 whole cell lysate (B).
WB
Western blot analysis of ANO1 expression in extracts of human skeletal muscle (A) and human liver tissues(B).
IHC
Immunoperoxidase staining of human gallbladder tissue fixed in formalin and embedded in paraffin reveals staining of glandular cell membrane and cytoplasm.| Application Notes | WB:1:100-1:1000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required. |
| Storage Buffer | Each vial contains 200 µg IgG2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. |
