WB
Western blot analysis of extracts of MB435 cell lines, using HAMP antibody.| Product Name | HAMP Polyclonal Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant protein of Human HAMP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HAMP |
|---|---|
| Gene Synonyms | HEPC PLTR HFE2B LEAP1 |
| Gene Full Name | hepcidin antimicrobial peptide |
| Gene Summary | The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity against bacteria and fungi. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Oct 2014] |
| Alternative Names | Hamp antibody HEPC antibody HEPC_HUMAN antibody Hepc20 antibody Hepc25 antibody HEPCIDIN antibody Hepcidin 20 antibody Hepcidin 25 antibody Hepcidin antimicrobial peptide antibody Hepcidin-20 antibody Hepcidin25 antibody HFE2 antibody HFE2B antibody LEAP 1 antibody LEAP-1 antibody LEAP1 antibody Liver expressed antimicrobial peptide antibody Liver-expressed antimicrobial peptide 1 antibody PLTR antibody Putative liver tumor regressor antibody |
| Molecular Weight(MW) | 10kDa |
| Cellular Localization | Secreted. |
WB
Western blot analysis of extracts of MB435 cell lines, using HAMP antibody.| Application Notes | WB:1:500-1:2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
