Recombinant Mycobacterium tuberculosis lprG protein (27-236aa ).
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
WB:1:2000 ELISA:1:1000-1:10000
Species Reactivity
Human
Concentration
1mg/ml
Purification
Protein G
Target Information
Gene Symbol
lprG
Gene Full Name
lipoarabinomannan carrier protein LprG
Alternative Names
Lipoarabinomannan carrier protein LprG (27 kDa lipoprotein) (Antigen P27) (Lipoprotein LprG) (Triacylglyceride transfer protein LprG) lprG lpp-27
Molecular Weight(MW)
32kDa
Function
Probably helps membrane protein MT1454 (P55) transport triacylglycerides (TAG) across the inner cell membrane into the periplasm and probably ultimately to the outer membrane. TAG probably regulates lipid metabolism and growth regulation. Binds di- and triacylated phosphatidyl-myo-inositol mannosides (PIMs), and glycolipid lipoglycan modulins lipoarabinomannan (LAM) and lipomannan (LM), facilitating their recognition by TLR2. Required for activity of drug efflux transporter MT1454. Required, probably with MT1454, for normal surface localization of LAM.; Constitutes a host TLR2 agonist (toll-like receptor).
Application
WB
Positive WB detected in Recombinant protein,
All lanes: lprG antibody at 1:2000,
Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution.
Application Notes
WB:1:2000 ELISA:1:1000-1:10000
Additional Information
Form
Liquid
Storage Instructions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.