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Rabbit anti-FKRP Polyclonal antibody

Catalog Number:OM645042
OM645042
Discount Price
OM645042-100ul
100ul
OM645042-50ul
50ul
Product Profile
Product Name Rabbit anti-FKRP Polyclonal antibody
Antibody Type Primary Antibodies
Immunogen Recombinant Human Fukutin-related protein (28-140AA).
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHC
IHC:1:200-1:500
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol FKRP
Gene Synonyms FKTR
MDC1C
LGMD2I
LGMDR9
MDDGA5
MDDGB5
MDDGC5
Gene Full Name fukutin related protein
Gene Summary This gene encodes a protein which is targeted to the medial Golgi apparatus and is necessary for posttranslational modification of dystroglycan. Mutations in this gene have been associated with congenital muscular dystrophy, cognitive disability, and cerebellar cysts. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2008]
Alternative Names Fkrp antibody
FKRP_HUMAN antibody
FLJ12576 antibody
Fukutin related protein antibody
Fukutin-related protein antibody
LGMD2I antibody
MDC1C antibody
MGC2991 antibody
Cellular Localization Golgi apparatus membrane; Single-pass type II membrane protein. Secreted. Cell membrane, sarcolemma. Rough endoplasmic reticulum. Cytoplasm.
Application

IHC

IHC image of FKRP Antibody diluted at 1:400 and staining in paraffin-embedded human ovarian cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IHC

IHC image of FKRP Antibody diluted at 1:400 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Application Notes IHC:1:200-1:500
Additional Information
Form Liquid
Storage Instructions Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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