WB
Various whole cell lysates were separated by 4-8% SDS-PAGE, and the membrane was blotted with anti-LRRK2 antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody. Lane 1: A549, Lane 2: NIH-3T3.IHC
Human kidney was stained with anti-LRRK2 Rabbit antibody.| Product Name | LRRK2 Rabbit mAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:1000-1:5000 IHC:1:500-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | LRRK2 |
|---|---|
| Gene Synonyms | PARK8 RIPK7 ROCO2 AURA17 DARDARIN |
| Gene Full Name | leucine rich repeat kinase 2 |
| Gene Summary | This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008] |
| Molecular Weight(MW) | 286kDa |
| Cellular Localization | Cytoplasmic vesicle . Perikaryon . Golgi apparatus membrane ; Peripheral membrane protein . Cell projection, axon . Cell projection, dendrite . Endoplasmic reticulum membrane ; Peripheral membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane . Endosome . Lysosome . Mitochondrion outer membrane ; Peripheral membrane protein . |
WB
Various whole cell lysates were separated by 4-8% SDS-PAGE, and the membrane was blotted with anti-LRRK2 antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody. Lane 1: A549, Lane 2: NIH-3T3.
IHC
Human kidney was stained with anti-LRRK2 Rabbit antibody.| Application Notes | WB:1:1000-1:5000 IHC:1:500-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Storage Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA. |
