WB
Western Blot analysis of 293 cells using GDF-5 Polyclonal Antibody. Secondary antibody was diluted at 1:20000.WB
Western blot analysis of lysate from 293 cells, using GDF5 Antibody.IHC
Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100.IHC
Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100.| Product Name | GDF-5 Rabbit pAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human GDF5. AA range:361-410. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | GDF5 |
|---|---|
| Gene Synonyms | OS5 LAP4 BDA1C BMP14 CDMP1 LAP-4 SYM1B SYNS2 BMP-14 DUPANS |
| Gene Full Name | growth differentiation factor 5 |
| Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis. [provided by RefSeq, Aug 2016] |
| Alternative Names | GDF5 CDMP1 Growth/differentiation factor 5 GDF-5 Cartilage-derived morphogenetic protein 1 CDMP-1 Radotermin |
| Molecular Weight(MW) | 55kDa |
| Cellular Localization | Secreted . Cell membrane . |
WB
Western Blot analysis of 293 cells using GDF-5 Polyclonal Antibody. Secondary antibody was diluted at 1:20000.
WB
Western blot analysis of lysate from 293 cells, using GDF5 Antibody.
IHC
Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100.
IHC
Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100.| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Storage Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA. |
