WB
Expression of STEAP3 in GC-2 cells treated with different concentrations of PS NPs (0, 100 µg/mL) for 12 hours.IHC
STEA3 Antibody at 1/100 staining mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-rabbit antibody was used as the secondary antibody.| Product Name | Rabbit polyclonal antibody to STEA3 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | A synthesized peptide derived from human STEA3, corresponding to a region within N-terminal amino acids. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:500-1:2000 IHC:1:50-1:200 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | STEAP3 |
|---|---|
| Gene Synonyms | STMP3 TSAP6 pHyde AHMIO2 dudlin-2 dudulin-2 |
| Gene Full Name | STEAP3 metalloreductase |
| Gene Summary | This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] |
| Alternative Names | 1010001D01Rik Dudlin 2 Dudlin2 Dudulin 2 Dudulin-2 Dudulin2 hpHyde hTSAP6 Metalloreductase STEAP3 MGC93147 pHyde Six transmembrane epithelial antigen of prostate 3 Six transmembrane prostate protein 3 Six-transmembrane epithelial antigen of prostate 3 STEA 3 STEA3_HUMAN STEAP 3 STEAP family member 3 STEAP family member 3 metalloreductase STEAP3 STMP 3 STMP3 TSAP 6 TSAP6 Tumor suppressor activated pathway protein 6 Tumor suppressor pHyde Tumor suppressor-activated pathway protein 6 |
| Molecular Weight(MW) | 54kDa |
| Cellular Localization | Endosome membrane>Multi-pass membrane protein. |
WB
Expression of STEAP3 in GC-2 cells treated with different concentrations of PS NPs (0, 100 µg/mL) for 12 hours.
IHC
STEA3 Antibody at 1/100 staining mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-rabbit antibody was used as the secondary antibody.| Application Notes | WB:1:500-1:2000 IHC:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 °C. Stable for 12 months from date of receipt. |
| Storage Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
