WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Tyk2 (Phospho Tyr1054/1055) antibody. The HRP-conjugated Goat anti-Rabbit IgG (H+L) antibody was used to detect the antibody. Lane 1: U266B1, Lane 2: U266B1 was treated with INF-α(10ng/ml) for 15 minutes .| Product Name | Tyk2 (Phospho Tyr1054/1055) Rabbit mAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification | p-Tyr1054/1055 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:10000-1:50000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | TYK2 |
|---|---|
| Gene Synonyms | JTK1 IMD35 |
| Gene Full Name | tyrosine kinase 2 |
| Gene Summary | This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with Immunodeficiency 35. [provided by RefSeq, Sep 2020] |
| Alternative Names | TYK2 Non-receptor tyrosine-protein kinase TYK2 |
| Molecular Weight(MW) | 134 kDa |
| Cellular Localization | nucleus,cytoplasm,cytosol,cytoskeleton,membrane,extrinsic component of cytoplasmic side of plasma membrane,extracellular exosome. |
WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Tyk2 (Phospho Tyr1054/1055) antibody. The HRP-conjugated Goat anti-Rabbit IgG (H+L) antibody was used to detect the antibody. Lane 1: U266B1, Lane 2: U266B1 was treated with INF-α(10ng/ml) for 15 minutes .| Application Notes | WB:1:10000-1:50000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Storage Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA. |
