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Polyclonal Antibody to Protocadherin Beta 2 (PCDHb2)

Catalog Number:OM645622
OM645622
Discount Price
OM645622-100ul
100ul
Product Profile
Product Name Polyclonal Antibody to Protocadherin Beta 2 (PCDHb2)
Antibody Type Primary Antibodies
Immunogen Recombinant PCDHb2 (Leu54~Arg291) expressed in E.coli
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCWB
IHC::5-20µg/mL
WB:1:200-1:2000
Species Reactivity Human
Concentration 0.5mg/ml
Purification Affinity purified
Target Information
Gene Symbol PCDHGB2
Gene Synonyms PCDH-GAMMA-B2
Gene Full Name protocadherin gamma subfamily B, 2
Gene Summary This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
Alternative Names PCDH-B2
Molecular Weight(MW) 27 kDa
Application

WB

Western Blot; Sample: Recombinant PCDHb2, Human.

IHC

DAB staining on IHC-P; Samples: Human Kidney Tissue; Primary Ab: 20µg/ml Rabbit Anti-Human PCDHb2 Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.

IHC

DAB staining on IHC-P;Sample: Porcine Cerebrum Tissue.
Application Notes IHC::5-20µg/mL
WB:1:200-1:2000
Additional Information
Form Liquid
Storage Instructions Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months.
Storage Buffer Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol.
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