WB
Western blot analysis of in vitro synthesized human TRβ1 (A-C) and TRα1 (D-F) prepared from TNT T7 programmed lysates. 1 µl (A,D),3 µl (B,E) and 6 µl (C,F).| Product Name | Mouse Monoclonal antibody to TRα1/β1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | raised against the ligand binding domain of the thyroid hormone receptor a1 of human origin. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1, k |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:100-1:1000 |
|
| Species Reactivity | Human |
| Concentration | 0.1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | THRB |
|---|---|
| Gene Synonyms | TRb GRTH PRTH THR1 ERBA2 NR1A2 THRB1 THRB2 TRbeta THRbeta TRbeta1 C-ERBA-2 THRbeta1 Thrbeta2 C-ERBA-BETA |
| Gene Full Name | thyroid hormone receptor beta |
| Gene Summary | The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008] |
| Molecular Weight(MW) | 47/58 kDa |
| Cellular Localization | Nucleus |
WB
Western blot analysis of in vitro synthesized human TRβ1 (A-C) and TRα1 (D-F) prepared from TNT T7 programmed lysates. 1 µl (A,D),3 µl (B,E) and 6 µl (C,F).| Application Notes | WB:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required. |
| Storage Buffer | Each vial contains 200 µg IgG1 kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. |
