Recombinant LOR (Ser210~Lys312) expressed in E.coli
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCWB
IHC:5-20µg/mL WB:1:200-1:2000
Species Reactivity
Human
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
LOXL2
Gene Synonyms
LOR LOR2 WS9-14
Gene Full Name
lysyl oxidase like 2
Gene Summary
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]
Molecular Weight(MW)
37 kDa
Application
WB
Western Blot; Sample: Recombinant LOR, Human.
IHC
DAB staining on IHC-P; Samples:Human Kidney Tissue; Primary Ab:10µg/ml Rabbit Anti-Human LOR,Antibody Second Ab: 2µg/mL HRPLinked Caprine Anti-Rabbit IgG
Polyclonal Antibody.
Application Notes
IHC:5-20µg/mL WB:1:200-1:2000
Additional Information
Form
Liquid
Storage Instructions
Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months.
Storage Buffer
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol.