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Polyclonal Antibody to Loricrin (LOR)

Catalog Number:OM645642
OM645642
Discount Price
OM645642-100ul
100ul
Product Profile
Product Name Polyclonal Antibody to Loricrin (LOR)
Antibody Type Primary Antibodies
Immunogen Recombinant LOR (Ser210~Lys312) expressed in E.coli
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCWB
IHC:5-20µg/mL
WB:1:200-1:2000
Species Reactivity Human
Concentration 0.5mg/ml
Purification Affinity purified
Target Information
Gene Symbol LOXL2
Gene Synonyms LOR
LOR2
WS9-14
Gene Full Name lysyl oxidase like 2
Gene Summary This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 37 kDa
Application

WB

Western Blot; Sample: Recombinant LOR, Human.

IHC

DAB staining on IHC-P; Samples:Human Kidney Tissue; Primary Ab:10µg/ml Rabbit Anti-Human LOR,Antibody Second Ab: 2µg/mL HRPLinked Caprine Anti-Rabbit IgG Polyclonal Antibody.
Application Notes IHC:5-20µg/mL
WB:1:200-1:2000
Additional Information
Form Liquid
Storage Instructions Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months.
Storage Buffer Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol.
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