| Product Name | Myc tag Mouse mAb, AE conjugated |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | KLH conjugated C-EQKLISEEDL |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | ELISA |
| ELISA:1:500-1:5000 |
|
| Species Reactivity | All |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MYC |
|---|---|
| Gene Synonyms | MRTL MYCC c-Myc bHLHe39 |
| Gene Full Name | MYC proto-oncogene, bHLH transcription factor |
| Gene Summary | This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017] |
| Alternative Names | MYC_HUMAN avian myelocytomatosis viral oncogene homolog bHLHe39 c-Myc class E basic helix-loop-helix protein 39 MRTL MYC Myc Epitope Tag myc proto-oncogene protein myc-related translation/localization regulatory factor oncogene c-Myc proto-oncogene c-Myc protooncogene homologous to myelocytomatosis virus transcription factor p64 v-myc avian myelocytomatosis viral oncogene homolog v-myc myelocytomatosis viral oncogene homolog(avian). |
| Cellular Localization | Nucleus. |
| Application Notes | ELISA:1:500-1:5000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
