| Product Name | Anti-Influenza A virus Matrix protein 1 Polyclonal Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | E. coli - derived recombinant Influenza A virus (Flu A/H10N7) Matrix protein 1 (Met1-Gln158). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| WB:1:500-1:2000 IHC:1:50-1:500 ELISA:1:1000-1:10000 |
|
| Species Reactivity | Virus |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Target | matrix protein 1, M1 |
|---|---|
| Function | Matrix protein 1 is a ~27 kDa protein. Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1, a non-raft-associated protein, into lipid rafts. Forms a continuous shell on the inner side of the lipid bilayer in virion, where it binds the RNP. |
| Application Notes | WB:1:500-1:2000 IHC:1:50-1:500 ELISA:1:1000-1:10000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
