WB
Western blot: All lanes: LIAS antibody at 2µg/ml. Lane 1: MCF-7 whole cell lysate. Lane 2: K562 whole cell lysate. Secondary: Goat polyclonal to rabbit IgG at 1/10000 dilution.IHC
Immunohistochemistry of paraffin-embedded human small intestine tissue using LIAS Antibody at dilution of 1:100| Product Name | Rabbit anti-LIAS Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant Human Lipoyl synthase, mitochondrial protein (28-372AA) |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:500-1:5000 IHC:1:20-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | LIAS |
|---|---|
| Gene Synonyms | LS LAS LIP1 PDHLD HGCLAS HUSSY-01 |
| Gene Full Name | lipoic acid synthetase |
| Gene Summary | The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. Localized in the mitochondrion, this iron-sulfur enzyme catalyzes the final step in the de novo pathway for the biosynthesis of lipoic acid, a potent antioxidant. The deficient expression of this enzyme has been linked to conditions such as diabetes, atherosclerosis and neonatal-onset epilepsy. Alternative splicing occurs at this locus, and several transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Aug 2020] |
| Alternative Names | LIAS antibody LAS antibody HUSSY-01Lipoyl synthase antibody mitochondrial antibody EC 2.8.1.8 antibody Lipoate synthase antibody LS antibody Lip-syn antibody Lipoic acid synthase antibody |
| Molecular Weight(MW) | 42,37,38 kDa(Observed band size: 42 kDa) |
| Cellular Localization | Mitochondrion. |
WB
Western blot: All lanes: LIAS antibody at 2µg/ml. Lane 1: MCF-7 whole cell lysate. Lane 2: K562 whole cell lysate. Secondary: Goat polyclonal to rabbit IgG at 1/10000 dilution.
IHC
Immunohistochemistry of paraffin-embedded human small intestine tissue using LIAS Antibody at dilution of 1:100| Application Notes | WB:1:500-1:5000 IHC:1:20-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
