Predicted to enable small GTPase binding activity. Predicted to be involved in cellular response to amino acid starvation; negative regulation of TORC1 signaling; and positive regulation of autophagy. Located in cytosol and perinuclear region of cytoplasm. Is expressed in branchial arch; genitourinary system; limb; and peripheral nervous system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy and familial focal epilepsy with variable foci 1. Orthologous to human DEPDC5 (DEP domain containing 5, GATOR1 subcomplex subunit). [provided by Alliance of Genome Resources, Apr 2025]
Alternative Names
DEP.5 FFEVF FPEVF FFEVF1
Molecular Weight(MW)
181 kDa
Application
WB
Western blot analysis of extracts from HCT116 cells using DEPDC5 Rabbit mAb at 1:1000.
Application Notes
WB:1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at -20°C.Stable for 12 months from date of receipt.
Storage Buffer
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA