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Mouse Monoclonal Antibody to CD81

Catalog Number:OM646082
OM646082
Discount Price
OM646082-100ul
100ul
OM646082-50ul
50ul
Product Profile
Product Name Mouse Monoclonal Antibody to CD81
Antibody Type Primary Antibodies
Immunogen Purified recombinant fragment of human CD81 (AA: 113-201) expressed in E. Coli.
Key Feature
Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications FCIHCWB
WB:1:500-1:2000
IHC:1:200-1:1000
FC:1:200-1:400
Species Reactivity HumanRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CD81
Gene Synonyms S5.7
CVID6
TAPA1
TSPAN28
Gene Full Name CD81 molecule
Gene Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Alternative Names S5.7
CVID6
TAPA1
TSPAN28
Molecular Weight(MW) 25.8 kDa
Cellular Localization Cell membrane,Membrane.
Application

WB

Western blot analysis using CD81 mouse mAb against Ramos (1), HEK293 (2),HepG2 (3), and C6 (4) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded human tonsil tissues using CD81 mouse mAb with DAB staining.

FC

Flow cytometric analysis of THP-1 cells using CD81 mouse mAb (green) and negative control (red).
Application Notes WB:1:500-1:2000
IHC:1:200-1:1000
FC:1:200-1:400
Additional Information
Form Liquid
Storage Instructions Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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