Recombinant Human Integrin beta-8 protein (43-320AA)
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCWB
WB:1:1000-1:5000 IHC:1:20-1:200
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
ITGB8
Gene Full Name
integrin subunit beta 8
Gene Summary
This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
Alternative Names
ITGB8 Integrin beta-8
Molecular Weight(MW)
86,72 kDa(Observed band size: 86 kDa)
Cellular Localization
Cell membrane; Single-pass type I membrane protein.
Application
WB
Western blot:All lanes: ITGB8 antibody at 1.52µg/ml.Secondary:Goat polyclonal to rabbit IgG at 1/10000 dilution.
IHC
Immunohistochemistry of paraffin-embedded human placenta tissue using anti-ITGB8 Antibody at dilution of 1:100
Application Notes
WB:1:1000-1:5000 IHC:1:20-1:200
Additional Information
Form
Liquid
Storage Instructions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.