WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-AID antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.IHC
Human tonsil was stained with anti-AID Rabbit antibody.| Product Name | AID Rabbit mAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG,K |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IHC:1:200-1:1000 WB:1:2000-1:10000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | AICDA |
|---|---|
| Gene Synonyms | AID ARP2 CDA2 HIGM2 HEL-S-284 |
| Gene Full Name | activation induced cytidine deaminase |
| Gene Summary | This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. AICDA is specifically expressed and active in germinal center-like B cells. In the germinal center, AICDA is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. An epigenetic role in neoplastic transformation and lymphoma progression has been experimentally ascribed to AICDA using mouse models. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Jul 2020] |
| Alternative Names | AICDA AID Activation-induced cytidine deaminase Cytidine aminohydrolase |
| Molecular Weight(MW) | 24 kDa (Observed band size: 23kDa) |
| Cellular Localization | Nucleus . Cytoplasm . Predominantly cytoplasmic (PubMed:21385873) . In the presence of MCM3AP/GANP , relocalizes to the nucleus (By similarity). |
WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-AID antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.
IHC
Human tonsil was stained with anti-AID Rabbit antibody.| Application Notes | IHC:1:200-1:1000 WB:1:2000-1:10000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Storage Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
