| Gene Symbol |
Ripk3
|
| Gene Synonyms |
Rip3 2610528K09Rik |
| Gene Full Name |
receptor-interacting serine-threonine kinase 3 |
| Gene Summary |
Enables protein serine/threonine kinase activity. Involved in several processes, including execution phase of necroptosis; hematopoietic or lymphoid organ development; and positive regulation of necroptotic process. Acts upstream of or within with a positive effect on non-canonical NF-kappaB signal transduction. Acts upstream of or within several processes, including positive regulation of intrinsic apoptotic signaling pathway; positive regulation of ligase activity; and regulation of reactive oxygen species metabolic process. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; immune system; male reproductive gland or organ; and turbinate bone primordium. Orthologous to human RIPK3 (receptor interacting serine/threonine kinase 3). [provided by Alliance of Genome Resources, Apr 2025] |
| Alternative Names |
Receptor interacting protein 3 Receptor interacting serine threonine kinase 3 Receptor interacting serine/threonine protein kinase 3 Receptor-interacting protein 3 Receptor-interacting serine/threonine-protein kinase 3 RIP 3 RIP like protein kinase 3 RIP-3 RIP-like protein kinase 3 RIPK 3 RIPK3 RIPK3_HUMAN
|
| Molecular Weight(MW) |
53 kDa(Observed band size: 57 kDa) |
| Cellular Localization |
Cytoplasm>Cytosol. Nucleus. |