WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Neurofascin antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.IHC
Mouse brain was stained with anti-Neurofascin Rabbit antibody..IHC
Rat brain was stained with anti-Neurofascin Rabbit antibody.IHC
Human brain was stained with anti-Neurofascin Rabbit antibody.| Product Name | Neurofascin Rabbit mAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG,K |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IHC:1:200-1:1000 WB:1:2000-1:10000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | NFASC |
|---|---|
| Gene Synonyms | NF NRCAML NEDCPMD |
| Gene Full Name | neurofascin |
| Gene Summary | This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.[provided by RefSeq, May 2009] |
| Molecular Weight(MW) | 138 kDa(Observed band size: 155 kDa) |
| Cellular Localization | Cell membrane ; Single-pass type I membrane protein .; [Isoform 8]: Cell junction , paranodal septate junction . |
WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Neurofascin antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.
IHC
Mouse brain was stained with anti-Neurofascin Rabbit antibody..
IHC
Rat brain was stained with anti-Neurofascin Rabbit antibody.
IHC
Human brain was stained with anti-Neurofascin Rabbit antibody.| Application Notes | IHC:1:200-1:1000 WB:1:2000-1:10000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Storage Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
